Title : Probing the mechanism and improving the rate of substrate-assisted catalysis in subtilisin BPN'.

Pub. Date : 1991 Jun 25

PMID : 2059622






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A mutant of the serine protease, subtilisin BPN", in which the catalytic His64 is replaced by Ala (H64A), is very specific for substrates containing a histidine, presumably by the substrate-bound histidine assisting in catalysis [Carter, P., & Wells, J.A. Histidine coagulation factor II, thrombin Homo sapiens
2 A mutant of the serine protease, subtilisin BPN", in which the catalytic His64 is replaced by Ala (H64A), is very specific for substrates containing a histidine, presumably by the substrate-bound histidine assisting in catalysis [Carter, P., & Wells, J.A. Histidine coagulation factor II, thrombin Homo sapiens