Title : Inhibition of gap junctional Intercellular communication in WB-F344 rat liver epithelial cells by triphenyltin chloride through MAPK and PI3-kinase pathways.

Pub. Date : 2010 Jun 30

PMID : 20591183






1 Functional Relationships(s)
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1 Pre-incubation of cells with the protein kinase C (PKC) inhibitor did not modify the response, but the specific MEK 1 inhibitor PD98059 and PI3K inhibitor LY294002 decreased substantially the inhibition of GJIC by TPTC. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen activated protein kinase kinase 1 Rattus norvegicus