Title : Celecoxib treatment restores pharmacosensitivity in a rat model of pharmacoresistant epilepsy.

Pub. Date : 2010 Jul

PMID : 20590600






1 Functional Relationships(s)
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1 EXPERIMENTAL APPROACH: Effects of the selective cyclooxygenase-2 inhibitor celecoxib on the response to the P-glycoprotein substrate, phenobarbital, was evaluated in a chronic model of drug-resistant temporal lobe epilepsy in rats. Phenobarbital ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus