Title : Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein.

Pub. Date : 2010 Sep 30

PMID : 20574048






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We found that both all-trans retinoic acid and arsenic trioxide induce autophagy via the mammalian target of rapamycin pathway in APL cells and that autophagic degradation contributes significantly both to the basal turnover as well as the therapy-induced proteolysis of PML/RARA. 2-octenal PML nuclear body scaffold Homo sapiens