Title : Signal transduction pathways associated with ATP-induced proliferation of colon adenocarcinoma cells.

Pub. Date : 2010 Sep

PMID : 20562007






1 Functional Relationships(s)
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1 Of physiological significance, in agreement with the mitogenic role of the MAPK cascade, ATP increased Caco-2 cell proliferation, and this effect was blocked by UO126, SB203580 and SP600125, the specific inhibitors of ERK1/2, p38 MAPK and JNK1/2, respectively. U 0126 mitogen-activated protein kinase 8 Homo sapiens