Title : A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity.

Pub. Date : 2010 Jul

PMID : 20558841






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The nicotinamide phosphoribosyl transferase (NAMPT) inhibitor APO866 (also called FK866 or WK175) selectively inhibits tumor growth through intracellular NAD depletion. WK175 nicotinamide phosphoribosyltransferase Mus musculus
2 The nicotinamide phosphoribosyl transferase (NAMPT) inhibitor APO866 (also called FK866 or WK175) selectively inhibits tumor growth through intracellular NAD depletion. WK175 nicotinamide phosphoribosyltransferase Mus musculus