Title : PTEN and p53 cross-regulation induced by soy isoflavone genistein promotes mammary epithelial cell cycle arrest and lobuloalveolar differentiation.

Pub. Date : 2010 Aug

PMID : 20554748






1 Functional Relationships(s)
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1 Our findings provide support to GEN-induced PTEN as both a target and regulator of p53 action and offer a mechanistic basis for PTEN pathway activation to underlie the antitumor properties of dietary factors, with important implications for reducing breast cancer risk. Genistein tumor protein p53 Homo sapiens