Title : Polyglutamine-expanded ataxin-7 upregulates Bax expression by activating p53 in cerebellar and inferior olivary neurons.

Pub. Date : 2010 Aug

PMID : 20546728






1 Functional Relationships(s)
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1 Our study provides the evidence that polyglutamine-expanded ataxin-7 upregulates the expression of Bax and Puma and causes apoptotic neuronal death by enhancing phosphorylation and transcriptional activity of p53. polyglutamine BCL2 binding component 3 Mus musculus