| Protein Name | BCL2 binding component 3 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 170770 |
| Gene Symbol | Bbc3 |
| UniProt | Q99ML1 (BBC3_MOUSE), B2RVL4 (B2RVL4_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
32
Total Number of Articles : 26 |
Description |
BCL2 binding component 3 |
| Gene Summary |
Predicted to enable ATPase binding activity. Involved in several processes, including determination of adult lifespan; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; and positive regulation of apoptotic process. Acts upstream of or within cellular response to ionizing radiation; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and positive regulation of apoptotic process. Predicted to be located in mitochondrial envelope. Predicted to be active in mitochondrion. Predicted to colocalize with lysosome. Is expressed in several structures, including central nervous system; immune system; liver; retina; and skeletal muscle. Orthologous to human BBC3 (BCL2 binding component 3). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
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| Properties | |