Title : IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation.

Pub. Date : 2010 Jul 31

PMID : 20530982






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Akt phosphorylation on Ser-473, which is catalyzed by mTOR and required for Akt activation, increased with increasing amounts of IQGAP1, and decreased with IQGAP1 mutation. Serine IQ motif containing GTPase activating protein 1 Homo sapiens
2 Akt phosphorylation on Ser-473, which is catalyzed by mTOR and required for Akt activation, increased with increasing amounts of IQGAP1, and decreased with IQGAP1 mutation. Serine IQ motif containing GTPase activating protein 1 Homo sapiens