Title : [New therapies targeting the genetic mutations responsible for different types of melanoma].

Pub. Date : 2010 Jun

PMID : 20525481






1 Functional Relationships(s)
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1 Sorafenib, a BRAF inhibitor, has a cytostatic effect on most melanomas with mutations affecting the mitogen-activated protein kinase (MAPK) pathway, and is also capable of triggering apoptosis in a small subgroup of these melanomas. Sorafenib B-Raf proto-oncogene, serine/threonine kinase Homo sapiens