Pub. Date : 2011 Jan
PMID : 20524040
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells. | Sunitinib | phosphatase and tensin homolog | Homo sapiens |
| 2 | Daoy and D556 human medulloblastoma cells pre-treated for 1 h with 0.2 muM sunitinib demonstrated induction of PTEN expression and significant inhibition of PDGFR signaling activity and transactivation of EGFR, in a RAS-independent manner, in response to PDGF-BB stimulation. | Sunitinib | phosphatase and tensin homolog | Homo sapiens |