Title : eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation.

Pub. Date : 2010 May 20

PMID : 20485439






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here we define new regulatory functions of eIF5 in the recycling of eIF2 from its inactive eIF2.GDP state between successive rounds of translation initiation. Guanosine Diphosphate eukaryotic translation initiation factor 5 Homo sapiens
2 First we show that eIF5 stabilizes the binding of GDP to eIF2 and is therefore a bi-functional protein that acts as a GDP dissociation inhibitor (GDI). Guanosine Diphosphate eukaryotic translation initiation factor 5 Homo sapiens
3 First we show that eIF5 stabilizes the binding of GDP to eIF2 and is therefore a bi-functional protein that acts as a GDP dissociation inhibitor (GDI). Guanosine Diphosphate eukaryotic translation initiation factor 5 Homo sapiens