Title : The adaptive compensations in endocrine pancreas from glucocorticoid-treated rats are reversible after the interruption of treatment.

Pub. Date : 2010 Nov

PMID : 20456283






4 Functional Relationships(s)
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1 Islets from DEX rats secreted more insulin in response to increasing concentrations of glucose and other metabolic and non-metabolic stimuli, compared with that in the CTL group. Dextromethorphan insulin Homo sapiens
2 The insulin secretion for the most compounds studied returned to CTL values in DEX(10) islets. Dextromethorphan insulin Homo sapiens
3 Increased insulin secretion correlated well with the augmentation in beta-cell proliferation and mass in DEX rats, and these morphological alterations were normalized in islets from DEX(10) rats. Dextromethorphan insulin Homo sapiens
4 Increased insulin secretion correlated well with the augmentation in beta-cell proliferation and mass in DEX rats, and these morphological alterations were normalized in islets from DEX(10) rats. Dextromethorphan insulin Homo sapiens