Title : Brain-derived neurotrophic factor redistribution in the dorsal root ganglia correlates with neuropathic pain inhibition after resiniferatoxin treatment.

Pub. Date : 2010 Aug

PMID : 20452292






3 Functional Relationships(s)
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1 Brain-derived neurotrophic factor redistribution in the dorsal root ganglia correlates with neuropathic pain inhibition after resiniferatoxin treatment. resiniferatoxin brain-derived neurotrophic factor Rattus norvegicus
2 A high-dose RTX injection in the DRG of neuropathic rats led to elimination of both thermal hyperalgesia and tactile allodynia and also upregulated BDNF in the large-size neurons, similar to the nonallodynic rats. resiniferatoxin brain-derived neurotrophic factor Rattus norvegicus
3 CONCLUSION: Resiniferatoxin injection in the DRG of neuropathic rats upregulates BDNF expression in the same pattern as in the large-size neurons of non-neuropathic rats. resiniferatoxin brain-derived neurotrophic factor Rattus norvegicus