Title : Thrombin promotes proinflammatory phenotype in human vascular smooth muscle cell.

Pub. Date : 2010 Jun 4

PMID : 20451499






1 Functional Relationships(s)
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1 Thrombin activated Akt, PKC and MAPK in HAoSMC, and thrombin-mediated expression of IL-6 and CXCL8 was significantly inhibited by LY294002, AKT IV, RO318220, and GF109203X as well as by diphenyleneiodium at the messenger RNA and the protein levels. Ro 31-8220 interleukin 6 Homo sapiens