Title : Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals.

Pub. Date : 2010 May 5

PMID : 20445064






1 Functional Relationships(s)
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1 More specifically, the mouse Wld(S) (Wallerian degeneration slow) protein, which is mainly composed of the full-length sequence of the NAD(+) biosynthetic Nmnat1 enzyme, can suppress dendritic pruning in C4da (class IV dendritic arborization) sensory neurons in parallel to the fly effector caspases. NAD nicotinamide nucleotide adenylyltransferase 1 Mus musculus