Title : Analgesic and anti-inflammatory actions of robenacoxib in acute joint inflammation in dog.

Pub. Date : 2010 Apr

PMID : 20444036






2 Functional Relationships(s)
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1 The objectives of this study were to establish dose-response and blood concentration-response relationships for robenacoxib, a novel nonsteroidal anti-inflammatory drug with selectivity for inhibition of the cyclooxygenase (COX)-2 isoenzyme, in a canine model of synovitis. robenacoxib cytochrome c oxidase subunit II Canis lupus familiaris
2 All dosages of robenacoxib produced significant dose-related inhibition of COX-2 (estimated ED(50) was 0.52 mg/kg) but no inhibition of COX-1. robenacoxib cytochrome c oxidase subunit II Canis lupus familiaris