Pub. Date : 2010 Apr
PMID : 20444036
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The objectives of this study were to establish dose-response and blood concentration-response relationships for robenacoxib, a novel nonsteroidal anti-inflammatory drug with selectivity for inhibition of the cyclooxygenase (COX)-2 isoenzyme, in a canine model of synovitis. | robenacoxib | cytochrome c oxidase subunit II | Canis lupus familiaris |
2 | All dosages of robenacoxib produced significant dose-related inhibition of COX-2 (estimated ED(50) was 0.52 mg/kg) but no inhibition of COX-1. | robenacoxib | cytochrome c oxidase subunit II | Canis lupus familiaris |