Pub. Date : 2010 Apr
PMID : 20424663
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | 7-ketocholesterol induces cell apoptosis by activation of nuclear factor kappa B in mouse macrophages. | 7-ketocholesterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
2 | Results showed that 7-KC-stimulation in J774A.1 cells activated NF-kappaB, which is involved in cell apoptosis, in a time- and dose-dependent manners. | 7-ketocholesterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
3 | Taken together, 7-KC may be an important factor in atherosclerosis due to the ability of 7-KC to induce cell apoptosis, which is at least partially mediated through the activation of NF-kappaB. | 7-ketocholesterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
4 | Taken together, 7-KC may be an important factor in atherosclerosis due to the ability of 7-KC to induce cell apoptosis, which is at least partially mediated through the activation of NF-kappaB. | 7-ketocholesterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |