Title : A versatile microbial system for biosynthesis of novel polyphenols with altered estrogen receptor binding activity.

Pub. Date : 2010 Apr 23

PMID : 20416510






1 Functional Relationships(s)
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1 Based on the determination of the substrate requirements of isoflavone synthase, a series of natural and nonnatural isoflavones were prepared and their binding affinities for the human estrogen receptors (ER alpha and ER beta) were determined. Isoflavones estrogen receptor 2 Homo sapiens