Title : Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway.

Pub. Date : 2010 Oct 1

PMID : 20413215






1 Functional Relationships(s)
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1 Furthermore, we found the dephosphorylation of Cdk1 at Thr161 induced by GA was abrogated, followed by a remarkable disruption of G2/M arrest when the cells were pre-incubated with caffeine. Caffeine cyclin dependent kinase 1 Homo sapiens