Title : Fatty acid synthase as a potential therapeutic target in cancer.

Pub. Date : 2010 Apr

PMID : 20373869






1 Functional Relationships(s)
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1 Early small-molecule FASN inhibitors such as cerulenin, C75 and orlistat have been shown to induce apoptosis in several cancer cell lines and to induce tumor growth delay in several cancer xenograft models but their mechanism is still not well understood. Cerulenin fatty acid synthase Homo sapiens