Title : Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death.

Pub. Date : 2010 Aug

PMID : 20371613






1 Functional Relationships(s)
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1 Our results showed that the selective A(2A) receptor agonist CGS21680 (EC(50)=15.2-32.6 nM) rescued mouse CD4(+) hybridomas and human Jurkat cells from AICD and that this effect was reversed by the selective A(2A) receptor antagonist ZM241385 (EC(50)=2.3 nM). 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine CD4 antigen Mus musculus