Title : Bcl-2 modulates resveratrol-induced ROS production by regulating mitochondrial respiration in tumor cells.

Pub. Date : 2010 Sep 15

PMID : 20367277






1 Functional Relationships(s)
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1 Whereas overexpression of Bcl-2 increased mitochondrial oxygen consumption and complex IV activity, CEM/Bcl-2 cells responded to the increased mitochondrial oxidative stress induced by resveratrol by significantly reducing mitochondrial respiration, complex IV activity, and O(2)(-) production, and promoted cell survival. Oxygen BCL2 apoptosis regulator Homo sapiens