Title : Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis.

Pub. Date : 2010 Jun 25

PMID : 20363741






1 Functional Relationships(s)
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1 Transforming growth factor (TGF)-beta1, a known inducer of EMT in epithelial cells, induces EMT in rat intestinal epithelial cells in vitro, and bone morphogenic protein-7, an antagonist of TGF-beta1, inhibits EMT and fibrosis both in vitro and in the TNBS-treated mice. Trinitrobenzenesulfonic Acid transforming growth factor, beta 1 Rattus norvegicus