Title : ROS leads to MnSOD upregulation through ERK2 translocation and p53 activation in selenite-induced apoptosis of NB4 cells.

Pub. Date : 2010 Jun 3

PMID : 20353787






2 Functional Relationships(s)
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1 Following our previous finding that sodium selenite induces apoptosis in human leukemia NB4 cells, we now show that the expression of the critical antioxidant enzyme manganese superoxide dismutase (MnSOD) is remarkably elevated during this process. Sodium Selenite superoxide dismutase 2 Homo sapiens
2 Following our previous finding that sodium selenite induces apoptosis in human leukemia NB4 cells, we now show that the expression of the critical antioxidant enzyme manganese superoxide dismutase (MnSOD) is remarkably elevated during this process. Sodium Selenite superoxide dismutase 2 Homo sapiens