Title : Sulindac metabolites induce proteosomal and lysosomal degradation of the epidermal growth factor receptor.

Pub. Date : 2010 Apr

PMID : 20332299






1 Functional Relationships(s)
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1 By contrast, downregulation of EGFR by sulindac sulfide and sulindac sulfone was first evident at 4 and 24 hours, respectively, with maximal downregulation at 72 hours. sulindac sulfone epidermal growth factor receptor Homo sapiens