Title : A second-order schedule of food reinforcement in rats to examine the role of CB1 receptors in the reinforcement-enhancing effects of nicotine.

Pub. Date : 2010 Oct

PMID : 20331564






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1 A second-order schedule of food reinforcement in rats to examine the role of CB1 receptors in the reinforcement-enhancing effects of nicotine. Nicotine cannabinoid receptor 1 Rattus norvegicus
2 Although endogenous cannabinoids acting on CB1 receptors have been implicated in the motivational effects of nicotine, their role in the "reinforcement-enhancing" properties of nicotine is unknown. Nicotine cannabinoid receptor 1 Rattus norvegicus
3 These data support and extend the hypothesis that nicotine can enhance the motivational value of reinforcing stimuli and suggest the increases in responding produced by nicotine involve CB1 receptors. Nicotine cannabinoid receptor 1 Rattus norvegicus