Title : Oxidative stress activates STAT1 in basilar arteries after subarachnoid hemorrhage.

Pub. Date : 2010 May 21

PMID : 20307504






4 Functional Relationships(s)
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1 The expression of STAT1 and p-STAT1 at Tyr(701) in basilar arteries was also examined by immunohistochemistry. Tyrosine signal transducer and activator of transcription 1 Rattus norvegicus
2 The expression of STAT1 and p-STAT1 at Tyr(701) in basilar arteries was also examined by immunohistochemistry. Tyrosine signal transducer and activator of transcription 1 Rattus norvegicus
3 Western blot analysis showed STAT1 to be significantly phosphorylated at Tyr(701) and Ser(727) within 2h of SAH and to gradually decrease thereafter. Tyrosine signal transducer and activator of transcription 1 Rattus norvegicus
4 Intracisternal injection of hydrogen peroxide, but not IL-6, also significantly increased phosphorylation of STAT1 at Tyr(701). Tyrosine signal transducer and activator of transcription 1 Rattus norvegicus