Title : Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells.

Pub. Date : 2010 Apr 1

PMID : 20305374






1 Functional Relationships(s)
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1 Celecoxib and MG132, both alone and synergistically in combination, induced expression of the endoplasmic reticulum (ER) stress genes ATF4, CHOP, TRB3 and promoted the splicing of XBP1 mRNA. Celecoxib DNA damage inducible transcript 3 Homo sapiens