Title : Alteration of in vivo zoxazolamine metabolism by carbon monoxide in normal and polycyclic hydrocarbon-treated immature male rats.

Pub. Date : 1977 Sep-Oct

PMID : 20293






1 Functional Relationships(s)
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1 The qualitative difference in response to CO exposure in the two groups of animals may be due to differences in the sensitivity of cytochrome P-450 and cytochrome P-448 with respect to complexing with CO or to lowered intracellular PO2; or to differences in the dependency on blood flow of the rate of in vivo metabolism of zoxazolamine. Zoxazolamine cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus