Title : Interaction of eight HIV protease inhibitors with the canalicular efflux transporter ABCC2 (MRP2) in sandwich-cultured rat and human hepatocytes.

Pub. Date : 2010 Mar

PMID : 20238377






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In human hepatocytes, saquinavir, ritonavir and atazanavir were the most efficient inhibitors of ABCC2-mediated biliary excretion of CDF, whereas in rat hepatocytes indinavir, lopinavir and nelfinavir were the most efficient. Nelfinavir ATP binding cassette subfamily C member 2 Homo sapiens