Pub. Date : 2010 Jul
PMID : 20238162
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Our results showed that Sal B significantly reduced the production of nitric oxide (NO), tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta) and reactive oxygen species (ROS) induced by lipopolysaccharide (LPS) treatment in rat primary microglia in a dose-dependent manner. | salvianolic acid B | tumor necrosis factor | Rattus norvegicus |
2 | Our results showed that Sal B significantly reduced the production of nitric oxide (NO), tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta) and reactive oxygen species (ROS) induced by lipopolysaccharide (LPS) treatment in rat primary microglia in a dose-dependent manner. | salvianolic acid B | tumor necrosis factor | Rattus norvegicus |
3 | Sal B also suppressed LPS-induced inducible nitric oxide synthase (iNOS), TNF-alpha, and IL-1beta mRNA expression, which was accompanied by inhibiting transcription factor NF-kappaB activation. | salvianolic acid B | tumor necrosis factor | Rattus norvegicus |