Title : Stimulation of lateral hypothalamic glutamate and acetylcholine efflux by nicotine: implications for mechanisms of nicotine-induced activation of orexin neurons.

Pub. Date : 2010 May

PMID : 20236223






2 Functional Relationships(s)
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1 We have previously shown that acute systemic nicotine treatment induces Fos expression in the lateral hypothalamus and perifornical area (LH/PFA), with orexin/hypocretin neurons being particularly responsive. Nicotine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 Lesioned animals showed reduced Fos-positive orexin neurons following nicotine treatment. Nicotine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus