Title : Pharmacokinetic and pharmacodynamic interactions between the immunosuppressant sirolimus and the lipid-lowering drug ezetimibe in healthy volunteers.

Pub. Date : 2010 Jun

PMID : 20220747






1 Functional Relationships(s)
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1 Organ transplant recipients who have dyslipidemia related to immunosuppression may benefit from cholesterol-lowering therapy with ezetimibe, a substrate of ABCB1, ABCC2, and OATP1B1. Cholesterol solute carrier organic anion transporter family member 1B1 Homo sapiens