Title : The metabolic enhancer piracetam ameliorates the impairment of mitochondrial function and neurite outgrowth induced by beta-amyloid peptide.

Pub. Date : 2010 May

PMID : 20218980






2 Functional Relationships(s)
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1 Similar protective effects against Abeta(1-42) were observed in dissociated brain cells from aged NMRI mice, or mice transgenic for mutant human amyloid precursor protein (APP) treated with piracetam for 14 days. Piracetam amyloid beta precursor protein Homo sapiens
2 Abeta production by HEK cells stably transfected with mutant human APP was elevated by oxidative stress and this was reduced by piracetam. Piracetam amyloid beta precursor protein Homo sapiens