Title : Genetic variants of XRCC1, APE1, and ADPRT genes and risk of bladder cancer.

Pub. Date : 2010 Jun

PMID : 20218899






2 Functional Relationships(s)
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1 We found an increased risk of bladder cancer associated with the XRCC1 194Trp/Trp and 280Arg/His genotypes (adjusted odds ratio = 3.90, 95% confidence interval = 1.69-8.98 for 194Trp/Trp and 2.53, 1.67-3.83 for 280Arg/His) compared with the 194Arg/Arg and 280Arg/Arg genotypes, respectively. Tryptophan X-ray repair cross complementing 1 Homo sapiens
2 We found an increased risk of bladder cancer associated with the XRCC1 194Trp/Trp and 280Arg/His genotypes (adjusted odds ratio = 3.90, 95% confidence interval = 1.69-8.98 for 194Trp/Trp and 2.53, 1.67-3.83 for 280Arg/His) compared with the 194Arg/Arg and 280Arg/Arg genotypes, respectively. Tryptophan X-ray repair cross complementing 1 Homo sapiens