Title : ROS-NFkappaB mediates TGF-beta1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion.

Pub. Date : 2010 Jul

PMID : 20204677






1 Functional Relationships(s)
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1 Our results shows that TGF-beta1 stimulation of uPA and MMP-9 expression involve NOXs-dependent ROS and NFkappaB, activation, demonstrated by using DPI, NOXs inhibitor, ROS scavenger N-acetylcysteine and SN50, an NFkb inhibitor. 3-aminodiphenyleneiodium matrix metallopeptidase 9 Homo sapiens