Title : Novel guggulsterone derivative GG-52 inhibits NF-kappaB signaling in intestinal epithelial cells and attenuates acute murine colitis.

Pub. Date : 2010 Jul

PMID : 20195240






1 Functional Relationships(s)
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1 Two guggulsterone derivatives, GG-50B and GG-52, significantly inhibited the activated NF-kappaB signals and the upregulated expression of interleukin-8 (IL-8) in COLO 205 cells stimulated with tumor necrosis factor-alpha (TNF-alpha). pregna-4,17-diene-3,16-dione tumor necrosis factor Mus musculus