Title : Erythropoietin increases expression and function of vascular copper- and zinc-containing superoxide dismutase.

Pub. Date : 2010 Apr

PMID : 20194292






2 Functional Relationships(s)
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1 In the present study, we hypothesized that EPO stimulates expression and activity of copper- and zinc-containing superoxide dismutase (SOD1), thus protecting vascular tissue from oxidative stress induced by excessive concentrations of superoxide anions. Superoxides superoxide dismutase 1, soluble Mus musculus
2 The ability of EPO to reduce vascular production of superoxide anions was abolished in SOD1-deficient mice. Superoxides superoxide dismutase 1, soluble Mus musculus