Title : Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.

Pub. Date : 2010 May 13

PMID : 20190804






1 Functional Relationships(s)
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1 A small fraction of a cell"s glucose enters the hexosamine biosynthetic pathway (HBP), which regulates levels of O-linked beta-N-acetylglucosamine (O-GlcNAc), a carbohydrate posttranslational modification of diverse nuclear and cytosolic proteins. Hexosamines O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens