Title : Effects of folate on arsenic toxicity in Chang human hepatocytes: involvement of folate antioxidant properties.

Pub. Date : 2010 May 19

PMID : 20188806






1 Functional Relationships(s)
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1 The results showed that folate deficiency significantly aggravated the NaAsO(2)-induced apoptotic progression [evidenced by phosphatidylserine externalization, cleavage of caspase-3 and poly (ADP-ribose) polymerase (PARP), collapse of mitochondrial potential, and release of cytochrome c from the mitochondria] and decrease of cell viability. sodium arsenite poly(ADP-ribose) polymerase 1 Homo sapiens