Pub. Date : 2010 Feb
PMID : 20187799
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our aim was to address that question by surveying the autophagic activity in parental lung adenocarcinoma cell line A549 and its 8-fold, more resistant subcell line, A549/DDP, which was obtained by treating cisplatin with increasing concentrations. | Cisplatin | translocase of inner mitochondrial membrane 8A | Homo sapiens |
| 2 | We also found that 3-MA can enhance the growth inhibition and apoptotic effect of cisplatin in acquired resistant cells (A549/DDP). | Cisplatin | translocase of inner mitochondrial membrane 8A | Homo sapiens |
| 3 | Collectively, our results provide evidence that the upregulation of autophagy plays a major role in cisplatin resistance of A549/DDP cells. | Cisplatin | translocase of inner mitochondrial membrane 8A | Homo sapiens |