PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20187799-2 2010 Our aim was to address that question by surveying the autophagic activity in parental lung adenocarcinoma cell line A549 and its 8-fold, more resistant subcell line, A549/DDP, which was obtained by treating cisplatin with increasing concentrations. Cisplatin 207-216 translocase of inner mitochondrial membrane 8A Homo sapiens 171-174 20187799-8 2010 We also found that 3-MA can enhance the growth inhibition and apoptotic effect of cisplatin in acquired resistant cells (A549/DDP). Cisplatin 82-91 translocase of inner mitochondrial membrane 8A Homo sapiens 126-129 20187799-9 2010 Collectively, our results provide evidence that the upregulation of autophagy plays a major role in cisplatin resistance of A549/DDP cells. Cisplatin 100-109 translocase of inner mitochondrial membrane 8A Homo sapiens 129-132