Title : Identification of functionally segregated sarcoplasmic reticulum calcium stores in pulmonary arterial smooth muscle.

Pub. Date : 2010 Apr 30

PMID : 20177054






1 Functional Relationships(s)
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1 Application of the vasoconstrictor endothelin-1 induced global Ca(2+) waves in pulmonary arterial smooth muscle cells, which were markedly attenuated upon depletion of SR Ca(2+) stores by preincubation of cells with the SERCA inhibitor thapsigargin but remained unaffected after preincubation of cells with a second SERCA antagonist, cyclopiazonic acid. cyclopiazonic acid endothelin 1 Homo sapiens