Pub. Date : 2009 Apr
PMID : 20169010
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Both the peroxisome proliferator-activated receptor delta agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol. | Cholesterol | peroxisome proliferator activator receptor delta | Mus musculus |
| 2 | Both the peroxisome proliferator-activated receptor delta agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol. | Cholesterol | peroxisome proliferator activator receptor delta | Mus musculus |
| 3 | Peroxisome proliferator-activated receptor delta (PPARdelta) agonism increases HDL cholesterol and has therefore the potential to stimulate macrophage-to-feces reverse cholesterol transport (RCT). | Cholesterol | peroxisome proliferator activator receptor delta | Mus musculus |
| 4 | Peroxisome proliferator-activated receptor delta (PPARdelta) agonism increases HDL cholesterol and has therefore the potential to stimulate macrophage-to-feces reverse cholesterol transport (RCT). | Cholesterol | peroxisome proliferator activator receptor delta | Mus musculus |
| 5 | Peroxisome proliferator-activated receptor delta (PPARdelta) agonism increases HDL cholesterol and has therefore the potential to stimulate macrophage-to-feces reverse cholesterol transport (RCT). | Cholesterol | peroxisome proliferator activator receptor delta | Mus musculus |
| 6 | Peroxisome proliferator-activated receptor delta (PPARdelta) agonism increases HDL cholesterol and has therefore the potential to stimulate macrophage-to-feces reverse cholesterol transport (RCT). | Cholesterol | peroxisome proliferator activator receptor delta | Mus musculus |
| 7 | In conclusion, PPARdelta activation enhances excretion of macrophage or HDL-derived cholesterol in feces through reduced NPC1L1 expression in mice, comparable to the effect of ezetimibe. | Cholesterol | peroxisome proliferator activator receptor delta | Mus musculus |