Pub. Date : 2010 Mar
PMID : 20168214
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Therefore, this study evaluated the effects of mecamylamine, a nAChR antagonist, on ethanol withdrawal signs. | Mecamylamine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 2 | In addition, chronic administration of mecamylamine into ethanol diet-fed mice markedly attenuated the ethanol withdrawal sign scores, thus supporting the contention that nAChR is involved in ethanol dependence. | Mecamylamine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 3 | In conclusion, our results suggest that mecamylamine exhibited inhibitory effects on ethanol withdrawal signs which could be mediated through nAChR. | Mecamylamine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |