Title : The switch of intestinal Slc26 exchangers from anion absorptive to HCOFormula secretory mode is dependent on CFTR anion channel function.

Pub. Date : 2010 May

PMID : 20164375






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A functionally active CFTR is an absolute requirement for Slc26-mediated duodenal HCO(3)(-) secretion, but not for Slc26-mediated fluid absorption, in which these transporters operate in conjunction with the Na(+)/H(+) exchanger NHE3. Bicarbonates cystic fibrosis transmembrane conductance regulator Mus musculus