Title : Human cytochrome p450c17: single step purification and phosphorylation of serine 258 by protein kinase a.

Pub. Date : 2010 Apr

PMID : 20160131






2 Functional Relationships(s)
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1 One factor favoring more efficient electron transfer and 17,20 lyase activity is cAMP-dependent serine/threonine phosphorylation of P450c17. Threonine cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 Using this vector, we explored P450c17 phosphorylation by mutagenesis of Ser and/or Thr residues to Asp or Glu to mimic the approximate size and charge of phospho-Ser or phospho-Thr. Threonine cytochrome P450 family 17 subfamily A member 1 Homo sapiens