Title : Site-specific mutagenesis of human interleukin-6 and its biological activity.

Pub. Date : 1991 Apr 9

PMID : 2015887






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Single substitution Met162----Ala and double substitutions Leu159.166----Val resulted in a significant decrease of IL-6 activity in the production of immunoglobulin (Ig) from B-cells. Valine interleukin 6 Homo sapiens